About Prepopik

Why PREPOPIK?

Experience the prep with the least medicine to drink (additional clear liquids required)

The colonoscopy prep is among the most common reasons people don’t undergo a colonoscopy. In fact, people may have told you that the worst part of their colonoscopy was the gallon of medicine they had to drink. Well, those stories probably weren’t about PREPOPIK.




Lowest volume of medicine

Unlike some colonoscopy preps that require you to drink liters or even a gallon of prep solution, PREPOPIK allows you to prep with:

  • 10 oz of prep solution (that’s less than a standard can of soda)
  • 64 oz of the approved clear liquids of your choice

See how the volume of PREPOPIK stacks up against other colonoscopy preps

Volume of active prep solution Total volume
PREPOPIK 10 oz glassblueglassblue 74 oz
Suprep® 32 oz glasswhiteglasswhiteglasswhiteglasswhite 96 oz
MoviPrep® 64 oz glasswhiteglasswhiteglasswhiteglasswhiteglasswhiteglasswhiteglasswhiteglasswhite 96 oz
HalfLytely® 64 oz + bisacodyl glasswhiteglasswhiteglasswhiteglasswhiteglasswhiteglasswhiteglasswhiteglasswhite 64 oz + bisacodyl
Suclear® 80 oz glasswhiteglasswhiteglasswhiteglasswhiteglasswhiteglasswhiteglasswhiteglasswhiteglasswhiteglasswhite 112 oz
4-liter PEG-based solution 128 oz glasswhiteglasswhiteglasswhiteglasswhiteglasswhiteglasswhiteglasswhiteglasswhite
glasswhiteglasswhiteglasswhiteglasswhiteglasswhiteglasswhiteglasswhiteglasswhite
128 oz
Efficacy and safety of products listed above may vary.

Preferred by patients in clinical trials

In the split-dose clinical trial, patients preferred PREPOPIK vs a comparator:

  • 99% of patients successfully finished their PREPOPIK regimen
  • 96% of patients would choose PREPOPIK again
  • 89% of patients found PREPOPIK to be very easy or easy to take

Split-dose: a colonoscopy prep that is taken the night before and morning of a colonoscopy.

The clinical trials evaluated adults preparing for a colonoscopy with PREPOPIK vs HalfLytely®. The main purpose of the trials was to evaluate how well bowel preparations worked. Secondarily, people in the trials were also asked to complete a questionnaire about orange-flavored PREPOPIK, which included the questions: “Would you ask your doctor for this preparation again if you needed another colonoscopy in the future” and “How easy or difficult was it to consume the prescribed bowel preparation?”

Cleaner colon for a clearer colonoscopy

PREPOPIK gave healthcare providers excellent or good visualization of the colon:

  • 84% of patients taking the split-dose regimen vs only 74% of those taking a comparator

Without a clean colon, your healthcare provider may have trouble seeing if there are signs of cancer during your colonoscopy. Read more about the importance of a clear colon and colonoscopy prep.

Select Safety Information
  • Do not take PREPOPIK if your healthcare provider has told you that you have serious kidney problems, a blockage in your intestine (bowel obstruction), an opening in the wall of your stomach or intestines (bowel perforation), a very dilated intestine (toxic megacolon), problems with the emptying of food and fluid from your stomach (gastric retention), or an allergy to any of the ingredients in PREPOPIK

Please see additional Important Safety Information.

See how PREPOPIK cleans specific parts of the colon

Of patients taking the split-dose regimen:

In clinical trials, patients preferred PREPOPIK vs a comparator:

  • 90% responded in the right side of the colon (ascending colon) vs only 79% of those taking a comparator
  • 92% responded in the top and left sides of the colon (mid-colon) vs only 86% of those taking a comparator
  • 92% responded in the short curving of the colon before the rectum (rectosigmoid) vs only 87% of those taking a comparator

Most common adverse reactions with PREPOPIK were nausea, headache, and vomiting.

Flexible timing

After each 5-oz dose of PREPOPIK, you have the ability to drink the required additional approved clear liquids at your own pace within 5 hours of taking the prep solution up until 2 hours before your colonoscopy.

Choice of flavors

Chances are you’ll never say, “Mmm, that colonoscopy prep was delicious.” But PREPOPIK has 2 flavors to choose from: Orange and Cranberry.

Testimonials

Patients and healthcare providers come clean about their experience with PREPOPIK

These testimonials reflect the experiences of the users who have provided the testimonials. Results referred to may not be typical and individual results may vary.

Andrew S.

Age:
50
Location:
Philadelphia, PA
Occupation:
Lawyer, Founder, Global Colon Cancer Association
Hobbies/Interests:
Spending time with family; doing things around the house
Colonoscopy History:
Multiple screenings over the last 15 years

“I lost my mom to stage 4 colon cancer in 1998. At the time, she was 64 and no one had recommended a colon cancer screening for her. Back then, there was no public conversation about colon cancer. I thought, ‘Where are the patient advocacy groups?’ So I found other people who felt the same way and we decided to form the Colon Cancer Alliance. I ran the organization as CEO from 2008 to 2013 and now I run the Global Colon Cancer Association.*

I remember my own experience with my first colonoscopy well. I’m happy to say that the results were normal and I’ve been getting screened regularly ever since. We’ve come a long way in the colonoscopy prep arena. Today we have low-volume prep options like PREPOPIK. I asked my doctor about it and he thought it would be right for me. When I woke up from my recent colonoscopy, he said everything was fine and he was pleased with how clean my colon was.

When people ask me about my experiences, I tell them about PREPOPIK. I suggest they ask their doctor about it and discuss which prep would be best for them. With this disease, you have the opportunity to prevent cancer through screening. You can’t say that about most other diseases.”

*The views expressed are the individual’s own and do not reflect the views of any organization with which he is or was affiliated.

Edward D.

Age:
59
Location:
Denver, CO
Occupation:
Professional Photographer
Hobbies/Interests:
Gardening, wine tasting
Colonoscopy History:
First colonoscopy

“I had my first colonoscopy when I was 58. I waited a long time. I think because of procrastination and fear. Maybe I was afraid that they’d find something that I didn’t want them to find. That’s the big fear, isn’t it, that we have cancer?

I wasn’t particularly looking forward to it. I’d heard stories about the preparation and how it’s a big deal.

So, I had a conversation with my doctor. I told him about my anxiety and specifically about that day of preparation. He prescribed PREPOPIK. The low volume was a big appeal.

My doctor had stressed the importance of that preparation day and I took it seriously. The instructions for PREPOPIK are straightforward. Two 5-oz doses of prep followed by additional approved clear liquids.

The outcome of my colonoscopy was great.

To someone who’s reluctant to have a colonoscopy, I would simply say: do it. Do it now. There’s no point in wasting time. There’s no reason to get cancer that is so preventable.”

Kim W.

Age:
50
Location:
Chesapeake Bay, MD
Occupation:
Medical Billing
Hobbies/Interests:
Being around the water, playing tennis, skiing, gardening
Colonoscopy History:
First colonoscopy

“I had a colonoscopy when I turned 50, because it’s recommended and my doctor wanted me to have it. I have a history of cancer in my family and I wanted to make sure I didn’t have cancer in the colon. I was being proactive about screening.

I had a lot of emotional reactions when it was time to get the colonoscopy and about the whole prep process—everyone talks about how horrible it is, how bad it tastes, how much prep there is.

My doctor told me to try PREPOPIK because it’s low volume. I drank the first 5 oz and then the additional approved clear liquids, and then I went to bed. The next morning, I drank my next 5 oz and my additional approved clear liquids.

According to my doctor, it was a successful colonoscopy. I was afraid of what it would feel like, but I just decided that it needed to be done. I’m glad I did it.”

John B.

Age:
68
Location:
Worcester, MA
Occupation:
Performing Artist/Realtor
Hobbies/Interests:
Biking, hiking, lead singer in a band
Colonoscopy History:
3 colonoscopies

“When my doctor told me that it was time to get my first colonoscopy, I hemmed and hawed a little bit about it. I said, ‘Well, do I really have to do this?’ The stories I heard were all about how bad the prep was.

When my doctor prescribed PREPOPIK for my last colonoscopy I went online to research it because I wanted to know what I was going to use. And I found that you take two 5-oz glasses of it, followed by approved clear liquids.

People have asked me why I like PREPOPIK and I said, ‘You don’t have to drink copious amounts of fluid.’ And that was a big attraction to me. With PREPOPIK, I could take it at my own pace. I didn’t have to drink it all at one sitting.

I’m going to ask my doctor if I can use PREPOPIK again. My friends say, ‘Why should I have a colonoscopy? Why should I go through that?’ Well, the fact of the matter is it’s not that bad. You should do it because it’s essential to good health.”

Dr. Franzese

Specialty:
Gastroenterologist
Location:
Chatham, NJ

 

“The most common fear, or perhaps misconception, about colonoscopy is how difficult the bowel preparation is. Bowel preps have become much more user-friendly. Now there are bowel preparations with smaller volume.

It’s important to realize that the bowel preparation is a very important part of the examination. The bowel preparation allows us to do a careful exam of the large intestine. We want to make sure that we do everything we can to see any colon polyps and sometimes they can be hard to see. We want to be able to say we’ve seen the entire bowel.

If my patients are candidates for using PREPOPIK, then I suggest that they use it. In fact, what I explain to them upfront is that PREPOPIK is the lowest volume bowel preparation on the market today.

When I prescribe PREPOPIK, I advise most patients to take the product as a Split-Dose regimen. They consume 5 oz of the solution, plus additional approved clear fluids, the day prior to the exam. Then they consume 5 oz of the solution, plus additional approved clear fluids, the morning of the exam.

They’re able to follow the directions and I’m able to see the colon clearly to do a full examination of the colon.”

Dr. Burrows

Specialty:
Gastroenterologist
Location:
Denver, CO

“Colonoscopies may save lives. A colonoscopy is used to look at the colon and make sure there are no precancerous growths, called polyps, that can turn into colon cancers. Colonoscopies are one of the only screening tests that we have that can actually prevent a cancer from developing.

Often patients are scared or skeptical about having a colonoscopy, especially about the bowel prep. The preps, historically, have been very uncomfortable. They can be as large as a gallon of fluid, and may be really difficult for people to consume.

I like to be able to offer my patients PREPOPIK, the lowest volume of active prep on the market. PREPOPIK is only 10 oz of active prep solution plus additional approved clear liquids. The overall feedback from my patients has been positive.

Given the prevalence of colon cancer, early detection is absolutely key. It’s very important that people see their doctor and get screened.”

Andrew S.

Find out why Andrew tells people about PREPOPIK.

Edward D.

Find out about Edward's experience with PREPOPIK.

Kim W.

Find out how Kim feels about PREPOPIK.

John B.

Find out why John would take PREPOPIK again.

Dr. Franzese

Find out why Dr. Franzese prescribes PREPOPIK.

Dr. Burrows

Find out why Dr. Burrows prescribes PREPOPIK for most of his patients.

Indication and Important Safety Information

PREPOPIK is a prescription medicine used by adults to clean the colon before a colonoscopy. PREPOPIK cleans your colon by causing you to have diarrhea. Cleaning your colon helps your healthcare provider see the inside of your colon more clearly during your colonoscopy.

  • Do not take PREPOPIK if your healthcare provider has told you that you have serious kidney problems, a blockage in your intestine (bowel obstruction), an opening in the wall of your stomach or intestines (bowel perforation), a very dilated intestine (toxic megacolon), problems with the emptying of food and fluid from your stomach (gastric retention), or an allergy to any of the ingredients in PREPOPIK
  • Tell your healthcare provider right away if you have any of these symptoms of a loss of too much body fluid (dehydration) while taking PREPOPIK: vomiting that prevents you from keeping down the additional prescribed amounts of clear liquids that you must drink after taking PREPOPIK, dizziness, urinating less often than normal, or headache
  • PREPOPIK and other bowel preparations can cause serious side effects, including serious loss of body fluid (dehydration) and changes in blood salts (electrolytes) in your blood. These changes can cause abnormal heartbeats that can cause death, seizures (this can happen even if you have never had a seizure), or kidney problems. Your chance of having fluid loss and changes in blood salts with PREPOPIK is higher if you have heart problems, have kidney problems, or take water pills or non-steroidal     anti-inflammatory drugs (NSAIDS). The most common side effects of PREPOPIK include nausea, headache, and vomiting

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Please see Full Prescribing Information.