about prepopik®
The Importance of a
Proper Prep

Colorectal cancer (CRC) is the 2nd leading cause for cancer-related deaths in the US. A colonoscopy can help prevent CRC through the detection of precancerous polyps. A colonoscopy can also be useful in the diagnosis and monitoring of gastrointestinal disorders like inflammatory bowel disease (IBD), Crohn’s disease, and ulcerative colitis.

Despite this, some people still avoid getting screened. Why? The colonoscopy prep can be a dreaded experience—with some preps requiring patients to drink up to a gallon of distasteful medicine.

Patients with IBD are at increased risk of developing CRC, and are advised to get colonoscopies every 1 to 3 years.

Why PREPOPIK®
Experience the prep with the least medicine to drink (additional clear liquids required)

Lowest volume of medicine

Unlike some colonoscopy preps that require you to drink liters or even a gallon of prep solution, PREPOPIK® allows you to prep with:

10 oz

of prep solution

+

Are you a healthcare provider? Discover How PREPOPIK® Works.

See how the volume of PREPOPIK® stacks up against other colonoscopy preps
Efficacy and safey of products listed above may vary.

Preferred by patients in a clinical trial

In a split-dose clinical trial, patients preferred PREPOPIK® vs a Day-Before comparator (2L PEG+E plus 2 X 5 mg bisacodyl tablets)*

99%

successfully finished their PREPOPIK® prescription

  • vs only 91% of patients who finished a comparator prep
96%

would choose PREPOPIK® again

  • vs only 55% of patients who would choose a comparator prep again
89%

found PREPOPIK® to be very easy or easy to take

  • vs only 29% of patients who found a comparator prep to be very easy or easy to take

Are you a healthcare provider? Read more about the Trial Designs. 

Split-dose: a colonoscopy prep that is taken the night before and morning of a colonoscopy.

*The clinical trials for Split-Dose and Day-Before Regimens evaluated adults preparing for a colonoscopy with PREPOPIK® vs a Day-Before comparator (2L PEG+E plus 2 X 5 mg bisacodyl tablets). The main purpose of the trials was to evaluate how well bowel preparations worked. People in the trials were also asked to complete a questionnaire about orange-flavored PREPOPIK®, which included the questions: “Would you ask your doctor for this preparation again if you needed another colonoscopy?” and “How easy or difficult was it to consume the prescribed bowel preparation?”

PREPOPIK® provides effective cleansing of the colon

PREPOPIK® gave healthcare providers excellent or good visualization of the overall colon in:

84%

of patients taking Split-Dose PREPOPIK® vs only 74% of those taking a Day-Before comparator

83%

of patients taking Day-Before PREPOPIK® vs only 80% of those taking a Day-Before comparator

The effectiveness of Split-Dose and Day-Before PREPOPIK® was studied in 2 clinical trials vs a Day-Before comparator (2L PEG+E plus 2 x 5 mg bisacodyl tablets).

The most common side effects with PREPOPIK® were nausea, headache, and vomiting.

Are you a healthcare provider? Learn more about Efficacy and Safety.

Select Safety Information

  • Do not take PREPOPIK® if your healthcare provider has told you that you have serious kidney problems, a blockage in your intestine (bowel obstruction), an opening in the wall of your stomach or intestines (bowel perforation), a very dilated intestine (toxic megacolon), problems with the emptying of food and fluid from your stomach (gastric retention), or an allergy to any of the ingredients in PREPOPIK®

Please see additional Important Safety Information.

Flexible timing

After each 5-oz dose of PREPOPIK®, drink the required additional recommended clear liquids (at your own pace) within 5 hours of taking the prep solution, up until 2 hours before your colonoscopy. Download the Step-by-Step Instructions or watch an Instructional Video.

Choice of flavors

PREPOPIK® has two flavors to choose from: Orange or Cranberry.

PREPOPIK® Testimonials
Patients and healthcare providers discuss their experience with PREPOPIK®
  • Andrew S.
  • AGE: 50
  • OCCUPATION: Lawyer; Founder, Global Colon Cancer Association
  • COLONSCOPY HISTORY: Multiple screenings over the last 15 years
  • Dr. Franzese
  • SPECIALTY: Gastroenterologist
  • LOCATION: Chatham, NJ
  • Kim W.
  • AGE: 50
  • OCCUPATION: Medical billing
  • COLONSCOPY HISTORY: First colonoscopy
  • Edward D.
  • AGE: 59
  • OCCUPATION: Professional photographer
  • COLONSCOPY HISTORY: First colonoscopy
  • Dr. Burrows
  • SPECIALTY: Gastroenterologist
  • LOCATION: Denver, CO
  • John B.
  • AGE: 68
  • OCCUPATION: Performing artist/Realtor
  • COLONSCOPY HISTORY: Three colonoscopies
PREPOPIK® FAQs
Is PREPOPIK® right for me?

It’s important to talk to your healthcare provider about your colonoscopy prep choices and to find out if PREPOPIK® is right for you. While you can certainly request PREPOPIK®, your healthcare provider will make that decision based on your medical history and what medications you may be taking.

How can I get PREPOPIK®?

PREPOPIK® is available by prescription only. Talk to your healthcare provider about using PREPOPIK® for your next colonoscopy.

PREPOPIK® also offers savings options! See how you can Save with PREPOPIK®.

How is PREPOPIK® different from other colonoscopy preps?
Lowest volume of medicine

PREPOPIK® lets you prep with:

  • 10 oz of medicine
  • 64 oz of the recommended clear liquids of your choice
Flexible timing

After each 5 oz dose of PREPOPIK®, drink the required additional recommended clear liquids (at your own pace) within 5 hours of taking the prep solution, up until 2 hours before your colonoscopy. Download the Step-by-Step Instructions or watch an Instructional Video.

Preferred by patients in clinical trials

In clinical trials, patients preferred PREPOPIK® vs a comparator (2L PEG + E plus 2 X 5 mg bisacodyl tablets)*

Choice of flavors

PREPOPIK® has two flavors to choose from: Orange or Cranberry.

The clinical trials for Split-Dose and Day-Before Regimens evaluated adults preparing for a colonoscopy with PREPOPIK® vs a Day-Before comparator (2L PEG+E plus 2 X 5 mg bisacodyl tablets). The main purpose of the trials was to evaluate how well bowel preparations worked. People in the trials were also asked to complete a questionnaire about orange-flavored PREPOPIK®, which included the questions: “Would you ask your doctor for this preparation again if you needed another colonoscopy?” and “How easy or difficult was it to consume the prescribed bowel preparation?”

Find out more about How PREPOPIK® Is Different.

What should my healthcare provider know before I take PREPOPIK®?

You should tell your healthcare provider about any medications you are taking, including, but not limited to, prescription and non-prescription medicines, vitamins, and herbal supplements, as well as about any ongoing medical conditions, including heart, kidney, and nervous system problems, or if you are pregnant or nursing.

Please see Full Prescribing Information including Patient Medication Guide for additional information.

How do I take PREPOPIK®?

Whether you’re taking Split-Dose or Day-Before PREPOPIK®, it’s important to follow the directions given to you by your healthcare provider. Download the Step-by-Step Instructions or watch an Instructional Video.

How does PREPOPIK® work?

Like all colonoscopy preps, PREPOPIK® causes diarrhea that, over time, cleans the solid waste from your colon.

If you’re a healthcare provider, learn more about How PREPOPIK® Works.

Can I eat while prepping with PREPOPIK®?

Starting the day before your procedure, you will only be able to consume clear liquids. Be sure to get exact instructions from your healthcare provider about what you can and cannot drink and how often you should drink during the colonoscopy prep.

For more information on taking PREPOPIK®, download the Step-by-Step Instructions or watch an Instructional Video.

How quickly does PREPOPIK® work?

Each patient reacts to PREPOPIK® differently. The effects of PREPOPIK® may be felt right away, or it may take some time. But it is important for you to stay close to a bathroom as soon as you begin taking PREPOPIK®.

What are the most common side effects?

The most common side effects associated with PREPOPIK® include nausea, headache, and vomiting. These are not all the possible side effects of PREPOPIK®.

Talk to your healthcare provider for more details about the potential risks and benefits of PREPOPIK® and to see if PREPOPIK® is right for you.

Please see Full Prescribing Information including Patient Medication Guide for additional information.

  • In a clinical trial, 96% of patients said they would take Split Dose PREPOPIK® again and 89% found it very easy or easy to take vs 55% and 29%, respectively, for a Day-Before comparator (2L PEG+E plus 2 x 5 mg bisacodyl tablets)
  • PREPOPIK® has been found effective as a bowel prep in both Split-Dose and Day-Before dosing regimens. Learn more

Indication and Important Safety Information

PREPOPIK® is a prescription medicine used by adults to clean the colon before a colonoscopy. PREPOPIK® cleans your colon by causing you to have diarrhea. Cleaning your colon helps your healthcare provider see the inside of your colon more clearly during your colonoscopy.

  • Do not take PREPOPIK® if your healthcare provider has told you that you have serious kidney problems, a blockage in your intestine (bowel obstruction), an opening in the wall of your stomach or intestines (bowel perforation), a very dilated intestine (toxic megacolon), problems with the emptying of food and fluid from your stomach (gastric retention), or an allergy to any of the ingredients in PREPOPIK®
  • Tell your healthcare provider right away if you have any of these symptoms of a loss of too much body fluid (dehydration) while taking PREPOPIK®: vomiting that prevents you from keeping down the additional prescribed amounts of clear liquids that you must drink after taking PREPOPIK®, dizziness, urinating less often than normal, or headache
  • PREPOPIK® and other bowel preparations can cause serious side effects, including serious loss of body fluid (dehydration) and changes in blood salts (electrolytes) in your blood. These changes can cause abnormal heartbeats that can cause death, seizures (this can happen even if you have never had a seizure), or kidney problems. Your chance of having fluid loss and changes in blood salts with PREPOPIK® is higher if you have heart problems, have kidney problems, or take water pills or non-steroidal anti-inflammatory drugs (NSAIDS)
  • The most common side effects of PREPOPIK® include nausea, headache, and vomiting. These are not all the possible side effects of PREPOPIK®

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.